COVID Testing & COVID Vaccine Updates:

June 12, 2021 Update from the June 7 version**

COVID Testing & COVID Vaccine Updates:
Note that most of the laboratory tests for COVID antibodies are specially designed to ONLY detect COVID antibodies from a natural COVID infectionv (the first topic discussed in this article) …

**The game has changed a bit, since we wrote the original June 7 version of the article:

If we now expand our descriptions of COVID testing to include the latest SPECIAL COVID antibody testing offered by BIOMÉDICOS DE MÉRIDA. Laboratorio de Análisis Clínicos … we now can get different setsd of separate results for Antibodies to “N-proteins” (Antibodies to Nucleocapsid SARS proteins) versus our levels of Antibodies to “S-proteins” (Antibodies to surface Spike SARS proteins) – allowing some distinctions between our COVID Antibodies from natural COVID infections versus vaccine-caused COVID antibodies:

https://www.facebook.com/BiomedicosDeMerida/posts/2135472383249799


So, yes, the new COVID Spike-protein Antibody test this one laboratory is now offering … is a game-changer.

“We are performing SARS CoV-2 IgG-IgM Antibody Profiling (nucleocapsid and spike), now with 𝗜𝗴𝗚 𝗖𝘂𝗮𝗻𝘁𝗶𝘁𝗮𝘁𝗶𝘃𝗮. It consists of: ▶ ️ Qualitative determination of Ac IgG (nucleocapsid) and IgM ▶ ️𝗖𝘂𝗮𝗻𝘁𝗶𝗳𝗶𝗰𝗮𝗰𝗶𝗼́𝗻 from Ac IgG Spike. The IgG antibody parameter 𝗰𝘂𝗮𝗻𝘁𝗶𝘁𝗮𝘁𝗶𝘃𝗼 selectively detects antibodies directed against the Spike protein of the virus. Since the vaccines in use target this specific protein, 𝙥𝙚𝙧𝙢𝙞𝙩𝙚 𝙢𝙚𝙙𝙞𝙧 𝙖𝙙𝙚𝙘𝙪𝙖𝙙𝙖𝙢𝙚𝙣𝙩𝙚 𝙡𝙖 𝙧𝙚𝙨𝙥𝙪𝙚𝙨𝙩𝙖 𝙞𝙣𝙢𝙪𝙣𝙚 𝙧𝙚𝙨𝙪𝙡𝙩𝙖𝙣𝙩𝙚 𝙩𝙧𝙖𝙨 𝙡𝙖 𝙫𝙖𝙘𝙪𝙣𝙖𝙘𝙞𝙤́𝙣, as well as the immune response resulting from a previous infection. Reports by: 📱 Inbox Fb Messenger 📧contacto@biomedicosdemerida.com 📞9999480750 / 9999433543

Note that the “S-protein” reference is for SARS-CoV-2 Spike protein (a surface protein that triggers both natural & vaccine based antibodies) … versus the “N-protein” reference for “Nucleocapsid” protein from the body of the virus that’s for natural vaccines & possibly some whole virus-vaccines, like the Sinovac.

Further note: Because Oxford-AstraZenica & Moderna & Pfizer have just spike protein pieces to trigger our antibody production … then comparing the N-protein Antibody results to the S-protein Antibody lab test results – is an good indication of the net numbers of antibodies you have from the vaccine.

People who got either Sinovac or Cansino vaccines can have a combination of S-protein Antibodies and/or N-protein Antibodies… So… The laboratory is still telling just a partial story, because we have such a variety of vaccines admistered here. Their claims very nicely fit the USA where just Moderna, Pfizer & JnJ spike protein based vaccines are used.
😉



Yucatan COVID Infection news from June, 7, 2021:
… As local cases of new COVID infections have more than tripled, it’s important to realize why COVID vaccies have significant gaps in their protection … as low as 50% protection for Oxford-AstraZenica … and as low as no protection for some 22% of elderly people just 6 months after their 2’nd Pfizer dose … (for vaccinated patients over age 80) … and Why we older folks need to keep wearing tight-fitting masks even after getting vaccinated …. See the second half of the article (below) for details.

Continuing with COVID Lab Test Information:
Notice that for COVID Antibody tests by many labs may not be useful to detect if your COVID vaccination is working: This means that when we get a COVID vaccine, then later if we get a Medical Doctor or laboratory to test us for COVID antibodies, the lab test will generally find … nothing. … unless you had a previous COVID infection … or unless you get the special “S-protein” (SARS Antibody Spike Protein) test … in combination with the “N-protein” (SARS Antibody Nucleocapsid protein) test.

Sadly, every Medical Doctor I have spoken with, so far, does not know these facts, because they generally have have very limited scientific training, and even less virology or laboratory training. Even more sad? Even the laboratory techs we’ve spoken with generally don’t know this. … It takes talking with either a good Laboratory Director, fine scientist, or excellent Pathologist to correctly answer these questions.


Why does the COVID antibody lab test too often NOT work for testing how many COVID antibodies your vaccine has triggered you to make?

The commonly offered COVID antibody lab test only checks for antibodies to a capsid protein … specifically a Coronavirus Nucleocapsid protein – aka “N protein”. … Meanwhile, the COVID vaccines are based on pieces of Coronavirus Spike proteins – aka “S protein”.


Why make a COVID antibody lab test that cannot measure the presence of antibodies from vaccines?

If the COVID antibody lab tests reacted to the vaccine caused antibodies, then everyone who got a vaccine would show up as FALSE POSITIVE lab tests for supposedly being infected with COVID.

Because we DO NOT WANT vaccinated people appearing to have active COVID infections in the lab tests, the clever laboratory scientists chose a protein-part of the Coronavirus (SARS CoV-2) virus that the vaccines do not incude – a Nucleocapsid protein from the body of the Coronavirus – that the vaccines miss. 😉


So … Ignore the mistaken FaceBook amateur dialogues where non-scientific people … and non*scientific Medical Doctors … mistakenly tell people to supposedly get COVID antibody tested to see how their vaccine is working. and instead read the description of both S-protein Antibodies AND N-Protein Antibodies tests at the beginning of this article. … 😉

**For people who do not know me (the author), I am a Doctor-Professor of Public Health and Laboratory Science with 45 yrs of professional experience in these areas … with a top Professora-Doctora Virologist wife who have decades of training in these things … things that Medical Doctors generally never study. 😉

And yes, despite typical Medical Doctors lack of knowledge in these areas, realize that these realities have been known by good scientists since last summer, 2020:

https://www.technologynetworks.com/diagnostics/blog/covid-19-antibody-testing-s-vs-n-protein-340327

and

https://www.news-medical.net/whitepaper/20210512/N-Protein-Variants-and-Their-Importance-in-Antibody-Test-and-Design.aspx

and

https://www.facebook.com/BiomedicosDeMerida/posts/2135472383249799


~ Stay well, stay informed, stay safe. ~



= = = = = = = = = = = = = = = = = = = = = = = = = = = = =
Yucatan COVID Infections Update:
This past week we had 1216 new confirmed COVID cases here.** This means Yucatan’s reported COVID cases have more than tripled from previous weekly lows down at 375 cases per week.

In spite of vaccinations, COVID Hospitalizations are also way up as of this Saturday, increasing from under 600 for several weeks ago … now rocketing up to over 1500 a week as of this past Saturday.

Estimates of Under-reporting of COVID cases in Yucatan State:
**Yucatan’s ongoing 10% death rates from COVID, roughly 10X higher than other countries, indicates that Yucatan’s COVID testing rates are so unusually low, that there are most-likely at least 10X more COVID cases than reported by the Government, meaning we likely have 12,000 – 20,000 COVID infected Yucatecans out running around in public right now => The highest rates seen in over a year.

Stay Safe using what’s proven to work!
Keep wearing your tight-fitting medical grade masks, as the world’s biggest vaccination study of 1.2 million Israelis shows up to a 12% failure rate for Pfizer vaccine when vaccinated people experience just incidental contact with COVID contagious people.

The rest of the story?
With 27% of COVID infected patients getting awful long-term health problems … and with significant numbers of vaccinated patients getting COVID infections (up to 12%) from just incidental contacts, we must continue wear tight-fitting medical grade masks & socially distancing. 😉

Vaccinations are very helpful, but they are NOT a magic bullet.

https://www.nejm.org/doi/full/10.1056/nejmoa2101765?fbclid=IwAR0xw2aBdk2mBlODdc97lk3LkKSQ51VnBZGaTvyMFatQvXuCskjcz2PDZg0


Why are COVID vaccines not a magic bullet?
Even the vaunted Pfizer vaccine gives just 88% protection from getting COVID from incidental contacts with COVID-infected people. 1 in 8 odds of getting COVID … Even worse, JnJ’s protection is down at just 65% … and even WORSE, Oxford-AstraZenica’s vaccine gives just 55% protection if you get your second dose of AstraZenica within 30 days of the first dose.**

Consider the consequences of rolling the dice on 1 in 8 odds of getting COVID after Pfizer vaccination … and 1 in 3 JnJ vaccinated people still get COVID from incidental contacts …

~ Over 1 in 4 COVID sufferors get nasty long term illnesses & permanent damage

… Brain damage, nervous system damage, lung damage, kidney damage, liver damage, cardiovascular damage.


~ Up to 22% of COVID infected Pfizer vaccinated people get “Serious COVID Disease” … from incidental exposure to COVID.


~ Up to 44% of Pfizer vaccinated people with “Serious COVID Disease” are hospitalized.
AND THEN:~ 6 months after Pfizer vaccinations, 23% – 1 in 4 elderly vaccinated patients HAVE NO MEMORY T-Cells against COVID… and NO KILLER-T Cells against COVID…

This means roughly 1 in 4 elderly people vaccinated with Pfizer … show antibodies to COVID … but have almost no immune system protection agaist actual COVID infections.

All these significant gaps & serious risks get even worse for JnJ vaccine, and even worse for Oxford-AstraZenica vaccine => Vaccination is NOT a magic bullet.

Vaccination is very helpful, but it is not the final answer if you care about your health … especially if you are over age 60.


** Note that Oxford-AstraZenica vaccine … the only vaccine available as of today, now in Yucatan … is ONLY 55% effective …. unless you wait 84 days between injections.Waiting 84 days between Oxford doses, increases the protection to just 76%…The State has been vaccinating people with the second Oxford dose just 1 month after the first jab => barely over 50% protection.


~ Stay well, stay informed, stay safe. ~


The Good Doctor Fry
Steven Michael Fry

Ph.D. Analytical Chemistry, Aerosol Science, Measurement Science, Public Health & Environment

Read On … MacDuff !

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4 Responses to COVID Testing & COVID Vaccine Updates:

  1. ~eric. says:

    Many thanks for keep us informed, Steve. Always edifying.

  2. Meir Gershenson says:

    I followed your earlier advise so in the last anual at LCM I added Covid immunity test:
    AC ANTI-SARS-CoV-2 (COVID-19) IgG
    METODO : QUIMIOLUMINISCENCIA
    357.00 AU/mL NEGATIVO: Menor de 12
    ZONA GRIS: 12 – 15
    POSITIVO: Igual o Mayor
    de 15
    I had both Pfizer more than two weeks earlier.

    • yucalandia says:

      The game has changed a bit, since I wrote the original article:

      If we now refer to the latest SPECIAL COVID antibody testing offered by BIOMÉDICOS DE MÉRIDA. Laboratorio de Análisis Clínicos, it gives a different set of separate results for Antibodies to “N-proteins” (Antibodies to Nucleocapsid SARS proteins) versus our levels of Antibodies to “S-proteins” (Antibodies to surface Spike SARS proteins).

      So, yes, the new COVID Spike-protein Antibody test they are now offering is a game-changer.

      “We are performing SARS CoV-2 IgG-IgM Antibody Profiling (nucleocapsid and spike), now with 𝗜𝗴𝗚 𝗖𝘂𝗮𝗻𝘁𝗶𝘁𝗮𝘁𝗶𝘃𝗮. It consists of: ▶ ️ Qualitative determination of Ac IgG (nucleocapsid) and IgM ▶ ️𝗖𝘂𝗮𝗻𝘁𝗶𝗳𝗶𝗰𝗮𝗰𝗶𝗼́𝗻 from Ac IgG Spike. The IgG antibody parameter 𝗰𝘂𝗮𝗻𝘁𝗶𝘁𝗮𝘁𝗶𝘃𝗼 selectively detects antibodies directed against the Spike protein of the virus. Since the vaccines in use target this specific protein, 𝙥𝙚𝙧𝙢𝙞𝙩𝙚 𝙢𝙚𝙙𝙞𝙧 𝙖𝙙𝙚𝙘𝙪𝙖𝙙𝙖𝙢𝙚𝙣𝙩𝙚 𝙡𝙖 𝙧𝙚𝙨𝙥𝙪𝙚𝙨𝙩𝙖 𝙞𝙣𝙢𝙪𝙣𝙚 𝙧𝙚𝙨𝙪𝙡𝙩𝙖𝙣𝙩𝙚 𝙩𝙧𝙖𝙨 𝙡𝙖 𝙫𝙖𝙘𝙪𝙣𝙖𝙘𝙞𝙤́𝙣, as well as the immune response resulting from a previous infection. Reports by: 📱 Inbox Fb Messenger 📧contacto@biomedicosdemerida.com 📞9999480750 / 9999433543 ”

      Note that the “S-protein” reference is for SARS-CoV-2 Spike protein (a surface protein that triggers both natural & vaccine based antibodies) … versus the “N-protein” reference for “Nucleocapsid” protein from the body of the virus that’s for natural vaccines & possibly some whole virus-vaccines, like the Sinovac.

      Further note: Because Oxford-AstraZenica & Moderna & Pfizer have just spike protein pieces to trigger our antibody production … then comparing the N-protein Antibody results to the S-protein Antibody lab test results – is an good indication of the net numbers of antibodies you have from the vaccine.

      People who got either Sinovac or Cansino vaccines can have a combination of S-protein Antibodies and/or N-protein Antibodies… So… The laboratory is still telling just a partial story, because we have such a variety of vaccines admistered here. Their claims very nicely fit the USA where just Moderna, Pfizer & JnJ spike protein based vaccines are used.
      😉

      Good to hear from you Meir … Lunch or Coffee …

      I’m now 50 days out from completing 2 Sinovac jabs… and 10 days out from completeing 2 jabs of Moderna vac.
      😉
      Steve

    • yucalandia says:

      Saying it another way, your results have utility … not just in the way we expected.

      If you get the Antibodies to SARS Spike proteins test now, you can compare the S-protein results to your basic basically negative “Nucleocapisid Antibody” test results. 😉

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